Psilocybin mushrooms have been used for hundreds, likely thousands of years. With at least 116 psilocybin active species known to date, their widespread occurrence and long history of use by numerous cultures has set the stage for modern medicine to measure their folklorically reported, therapeutic benefits. Currently, more than 40 universities in North America and Europe have been approved for clinical studies ranging from treating depression to Alzheimer’s to addiction, psilocybin has risen to the forefront of medical research. This talk will cover the psilocybin movement through history into the modern epoch. It offers an overview of the most clinically significant studies, the newest research on psilocybin analogs, micro-dosing, and the implications for creating a paradigm shift in the ecology of consciousness.  Will psilocybin help us be healthier, happier, and better Earth citizens? Could psilocybin be the tipping point in the next quantum leap in the evolution of humans? Let’s look at the evidence together for an informed discussion.